3beta-HSD7 rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: 3beta-HSD7 rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1548
• Supplier Catalog Number: ES1548
• Alternative Catalog Number: EBT-ES1548-50, EBT-ES1548-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human HSD3B7. AA range:121-170
• Alternative Names: HSD3B7, 3 beta-hydroxysteroid dehydrogenase type 7, 3 beta-hydroxysteroid dehydrogenase type VII, 3-beta-HSD VII, 3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase, C(27) 3-beta-HSD, Cholest-5-ene-3-beta, 7-alpha-diol 3-beta-dehydrogenase

Product Description

This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 41kD
• NCBI: 80270
• UniProt: Q9H2F3

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using 3beta-HSD7 Polyclonal Antibody diluted at 1:1000

Western Blot analysis of COLO205 cells using 3beta-HSD7 Polyclonal Antibody diluted at 1:1000

Western blot analysis of lysates from HeLa, MCF-7, and COLO cells, using HSD3B7 Antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of the lysates from Jurkat cells using HSD3B7 antibody.