Synthesized peptide derived from human FAN1 AA range: 801-851
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5 flap endonuclease and 5-3 exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],
