EGFR (Phospho-Tyr998) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: EGFR (Phospho-Tyr998) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES16782
• Supplier Catalog Number: ES16782
• Alternative Catalog Number: EBT-ES16782-50, EBT-ES16782-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human EGFR (Phospho-Tyr998)
• Alternative Names: Epidermal growth factor receptor (EC 2.7.10.1,Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1)

Product Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 175kD
• NCBI: 1956
• UniProt: P00533

Application Notes

• Application Dilute: IHC-p 1:50-200, WB 1:500-2000

Images

Immunohistochemical analysis of paraffin-embedded human colon cancer. 1, Tris-EDTA,pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200(4 overnight.3,Secondary antibody was diluted at 1:200(room temperature, 45min).