APRIL rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES1685
Article Name: APRIL rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES1685
Supplier Catalog Number: ES1685
Alternative Catalog Number: EBT-ES1685-50, EBT-ES1685-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: ELISA, IF, IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human TALL-2. AA range:151-200
Alternative Names: TNFSF13, APRIL, TALL2, ZTNF2, Tumor necrosis factor ligand superfamily member 13, A proliferation-inducing ligand, APRIL, TNF- and APOL-related leukocyte expressed ligand 2, TALL-2, TNF-related death ligand 1, TRDL-1, CD antigen CD256
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) ligand family. This protein is a ligand for TNFRSF17/BCMA, a member of the TNF receptor family. This protein and its receptor are both found to be important for B cell development. In vitro experiments suggested that this protein may be able to induce apoptosis through its interaction with other TNF receptor family proteins such as TNFRSF6/FAS and TNFRSF14/HVEM. Alternative splicing results in multiple transcript variants. Some transcripts that skip the last exon of the upstream gene (TNFSF12) and continue into the second exon of this gene have been identified, such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010],
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 23kD
NCBI: 8741
UniProt: O75888
Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Western Blot analysis of various cells using APRIL Polyclonal Antibody diluted at 1:2000
Western Blot analysis of COLO205 cells using APRIL Polyclonal Antibody diluted at 1:2000
Immunofluorescence analysis of HeLa cells, using TALL-2 Antibody. The picture on the right is blocked with the synthesized peptide.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TALL-2 Antibody. The picture on the right is blocked with the synthesized peptide.