AR-beta2 rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: AR-beta2 rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES1713
• Supplier Catalog Number: ES1713
• Alternative Catalog Number: EBT-ES1713-50, EBT-ES1713-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, FC, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor beta2. AA range:321-370
• Alternative Names: ADRB2, ADRB2R, B2AR, Beta-2 adrenergic receptor, Beta-2 adrenoreceptor, Beta-2 adrenoceptor

Product Description

This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 47kD
• NCBI: 154
• UniProt: P07550

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/5000. Not yet tested in other applications.

Images

Western Blot analysis of various cells using AR-beta2 Polyclonal Antibody

Immunofluorescence analysis of HeLa cells, using Adrenergic Receptor beta2 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Adrenergic Receptor beta2 Antibody. The picture on the right is blocked with the synthesized peptide.

Western blot analysis of lysates from NIH/3T3 cells, using Adrenergic Receptor beta2 Antibody. The lane on the right is blocked with the synthesized peptide.