Synthesized peptide derived from human ITGA3 (heavy chain, Cleaved-Phe33)
Alternative Names:
Integrin alpha-3 (CD49 antigen-like family member C,FRP-2,Galactoprotein B3,GAPB3,VLA-3 subunit alpha,CD antigen CD49c) [Cleaved into: Integrin alpha-3 heavy chain, Integrin alpha-3 light chain]
integrin subunit alpha 3(ITGA3) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function as cell surface adhesion molecules. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 3 subunit. This subunit joins with a beta 1 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. Expression of this gene may be correlated with breast cancer metastasis. [provided by RefSeq, Oct 2015],
Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).
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