ITGA2B (heavy chain, Cleaved-Leu32) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: ITGA2B (heavy chain, Cleaved-Leu32) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES20011
• Supplier Catalog Number: ES20011
• Alternative Catalog Number: EBT-ES20011-50, EBT-ES20011-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human ITGA2B (heavy chain, Cleaved-Leu32)
• Alternative Names: Integrin alpha-IIb (GPalpha IIb,GPIIb,Platelet membrane glycoprotein IIb,CD antigen CD41) [Cleaved into: Integrin alpha-IIb heavy chain, Integrin alpha-IIb light chain, form 1, Integrin alpha-IIb light chain, form 2]

Product Description

This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 95 110kD
• NCBI: 3674
• UniProt: P08514

Application Notes

• Application Dilute: WB 1:500-2000,IHC-p 1:50-300

Images

Immunohistochemical analysis of paraffin-embedded human meningioma. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).