MLK3 (Phospho Thr277+Ser281) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: MLK3 (Phospho Thr277+Ser281) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES20162
• Supplier Catalog Number: ES20162
• Alternative Catalog Number: EBT-ES20162-50, EBT-ES20162-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human MLK3 (Phospho Thr277+Ser281)
• Alternative Names: Mitogen-activated protein kinase kinase kinase 11 (EC 2.7.11.25,Mixed lineage kinase 3,Src-homology 3 domain-containing proline-rich kinase)

Product Description

The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 4296
• UniProt: Q16584

Application Notes

• Application Dilute: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000

Images

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).