PP2B-Aalpha rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: PP2B-Aalpha rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES20264
• Supplier Catalog Number: ES20264
• Alternative Catalog Number: EBT-ES20264-50, EBT-ES20264-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from human PP2B-Aalpha
• Alternative Names: Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16,CAM-PRP catalytic subunit,Calmodulin-dependent calcineurin A subunit alpha isoform)

Product Description

catalytic activity:A phosphoprotein + H(2)O = a protein + phosphate.,cofactor:Binds 1 Fe(3+) ion per subunit.,cofactor:Binds 1 zinc ion per subunit.,function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1.,online information:Calcineurin entry,similarity:Belongs to the PPP phosphatase family.,similarity:Belongs to the PPP phosphatase family. PP-2B subfamily.,subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle.,subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.,

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 5530
• UniProt: Q08209

Application Notes

• Application Dilute: WB 1:500-2000,IHC-p 1:50-300

Images

Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).