This gene is a member of the equilibrative nucleoside transporter family. The gene encodes a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium. The protein is categorized as an equilibrative (as opposed to concentrative) transporter that is sensitive to inhibition by nitrobenzylthioinosine (NBMPR). Nucleoside transporters are required for nucleotide synthesis in cells that lack de novo nucleoside synthesis pathways, and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008],
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Western Blot analysis of extracts from Jurkat, K562, NIH-3T3 cells, using ENT1 Polyclonal Antibody. Antibody was diluted at 1:2000. Secondary antibody(catalog:RS0002) was diluted at 1:20000
Western blot analysis of lysates from MDA-MB-435 cells, using ENT1 antibody.
* VAT and and shipping costs not included. Errors and price changes excepted
