Dkk-1 rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Dkk-1 rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4292
• Supplier Catalog Number: ES4292
• Alternative Catalog Number: EBT-ES4292-50, EBT-ES4292-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230
• Alternative Names: DKK1, Dickkopf-related protein 1, Dickkopf-1, Dkk-1, hDkk-1, SK

Product Description

This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 29kD
• NCBI: 22943
• UniProt: O94907

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

Images

Western Blot analysis of Hela cells using Dkk-1 Polyclonal Antibody. Secondary antibody(catalog:RS0002) was diluted at 1:20000

Immunohistochemical analysis of paraffin-embedded human-brain, antibody was diluted at 1:100