The antiserum was produced against synthesized peptide derived from the Internal region of human PVR. AA range:81-130
Alternative Names:
PVR, PVS, Poliovirus receptor, Nectin-like protein 5, NECL-5, CD155
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],
