Vav3 (phospho Tyr173) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Vav3 (phospho Tyr173) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4475
• Supplier Catalog Number: ES4475
• Alternative Catalog Number: EBT-ES4475-50, EBT-ES4475-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC, WB
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized phospho-peptide around the phosphorylation site of human Vav3 (phospho Tyr173)
• Alternative Names: VAV3, Guanine nucleotide exchange factor VAV3, VAV-3

Product Description

This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 100kD
• NCBI: 10451
• UniProt: Q9UKW4

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Images

Western Blot analysis of JK cells using Phospho-Vav3 (Y173) Polyclonal Antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).