A Cyclase VIII rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: A Cyclase VIII rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4642
• Supplier Catalog Number: ES4642
• Alternative Catalog Number: EBT-ES4642-50, EBT-ES4642-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human ADCY8. AA range:591-640
• Alternative Names: ADCY8, Adenylate cyclase type 8, ATP pyrophosphate-lyase 8, Adenylate cyclase type VIII, Adenylyl cyclase 8, AC8, Ca(2+)/calmodulin-activated adenylyl cyclase

Product Description

Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 114
• UniProt: P40145

Application Notes

• Application Dilute: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Images

Immunofluorescence analysis of A549 cells, using ADCY8 Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ADCY8 Antibody. The picture on the right is blocked with the synthesized peptide.