ACTR-IC rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: ACTR-IC rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4754
• Supplier Catalog Number: ES4754
• Alternative Catalog Number: EBT-ES4754-50, EBT-ES4754-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human ACTR-1C. AA range:201-250
• Alternative Names: ACVR1C, ALK7, Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7

Product Description

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 130399
• UniProt: Q8NER5

Application Notes

• Application Dilute: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Images

Immunofluorescence analysis of COS7 cells, using ACTR-1C Antibody. The picture on the right is blocked with the synthesized peptide.

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ACTR-1C Antibody. The picture on the right is blocked with the synthesized peptide.