CREB-1 (phospho Thr100) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: CREB-1 (phospho Thr100) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES4798
• Supplier Catalog Number: ES4798
• Alternative Catalog Number: EBT-ES4798-50, EBT-ES4798-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from human CREB around the phosphorylation site of Thr100. AA range:71-120
• Alternative Names: CREB1, Cyclic AMP-responsive element-binding protein 1, CREB-1, cAMP-responsive element-binding protein 1

Product Description

This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds as a homodimer to the cAMP-responsive element, an octameric palindrome. The protein is phosphorylated by several protein kinases, and induces transcription of genes in response to hormonal stimulation of the cAMP pathway. Alternate splicing of this gene results in several transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 42kD
• NCBI: 1385
• UniProt: P16220

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Images

Enzyme-Linked Immunosorbent Assay (Phospho-ELISA) for Immunogen Phosphopeptide (Phospho-left) and Non-Phosphopeptide (Phospho-right), using CREB (Phospho-Thr100) Antibody

Western blot analysis of lysates from HUVEC cells treated with etoposide 25uM 24H, using CREB (Phospho-Thr100) Antibody. The lane on the right is blocked with the phospho peptide.