Cleaved-Kininogen-1 HC (K380) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: Cleaved-Kininogen-1 HC (K380) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES6027
• Supplier Catalog Number: ES6027
• Alternative Catalog Number: EBT-ES6027-50,EBT-ES6027-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized peptide derived from Cleaved-Kininogen-1 HC (K380) . at AA range: 300-380
• Alternative Names: KNG1, BDK, KNG, Kininogen-1, Alpha-2-thiol proteinase inhibitor, Fitzgerald factor, High molecular weight kininogen, HMWK, Williams-Fitzgerald-Flaujeac factor

Product Description

This gene uses alternative splicing to generate two different proteins- high molecular weight kininogen (HMWK) and low molecular weight kininogen (LMWK). HMWK is essential for blood coagulation and assembly of the kallikrein-kinin system. Also, bradykinin, a peptide causing numerous physiological effects, is released from HMWK. Bradykinin also functions as an antimicrobial peptide with antibacterial and antifungal activity. In contrast to HMWK, LMWK is not involved in blood coagulation. Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2014],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 41kD
• NCBI: 3827
• UniProt: P01042

Application Notes

• Application Dilute: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.