GCN2 (phospho Thr899) rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: GCN2 (phospho Thr899) rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES6270
• Supplier Catalog Number: ES6270
• Alternative Catalog Number: EBT-ES6270-50, EBT-ES6270-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, IF, IHC
• Species Reactivity: Human, Mouse
• Immunogen: The antiserum was produced against synthesized peptide derived from human GCN2 around the phosphorylation site of Thr899. AA range:865-914
• Alternative Names: EIF2AK4, GCN2, KIAA1338, Eukaryotic translation initiation factor 2-alpha kinase 4, GCN2-like protein

Product Description

This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• NCBI: 440275
• UniProt: Q9P2K8

Application Notes

• Application Dilute: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Images

Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 30min).