The antiserum was produced against synthesized peptide derived from human HECW2. AA range:481-530
Alternative Names:
HECW2, KIAA1301, NEDL2, E3 ubiquitin-protein ligase HECW2, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2
function:E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73.,pathway:Protein modification, protein ubiquitination.,similarity:Contains 1 C2 domain.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 2 WW domains.,subunit:Interacts with TP73.,tissue specificity:Predominantly expressed in adult brain, lung and heart.,
