RBQ-3 rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES7008
Article Name: RBQ-3 rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES7008
Supplier Catalog Number: ES7008
Alternative Catalog Number: EBT-ES7008-50, EBT-ES7008-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from RBQ-3 . at AA range: 190-270
Alternative Names: RBBP5, RBQ3, Retinoblastoma-binding protein 5, RBBP-5, Retinoblastoma-binding protein RBQ-3
This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2010],
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 59kD
NCBI: 5929
UniProt: Q15291
Application Dilute: WB 1:500-2000,IHC-p 1:50-300
Western Blot analysis of CoLo cells using RBQ-3 Polyclonal Antibody cells nucleus extracted by Minute TM Cytoplasmic and Nuclear Fractionation kit (SC-003,Inventbiotech,MN,USA).
Immunohistochemical analysis of paraffin-embedded human Gastric adenocarcinoma. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).