RGS7 rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES7042
Article Name: RGS7 rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES7042
Supplier Catalog Number: ES7042
Alternative Catalog Number: EBT-ES7042-50,EBT-ES7042-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC, WB
Species Reactivity: Human, Mouse, Rat
Immunogen: The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204
Alternative Names: RGS7, Regulator of G-protein signaling 7, RGS7
function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations.,PTM:Palmitoylated.,PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity.,similarity:Contains 1 DEP domain.,similarity:Contains 1 G protein gamma domain.,similarity:Contains 1 RGS domain.,subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.,
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 65kD
NCBI: 6000
UniProt: P49802
Application Dilute: WB 1:500-2000,IHC-p 1:50-300, ELISA 2000-20000