C8 beta rabbit pAb, Rabbit, Polyclonal

Product Overview

• Article Name: C8 beta rabbit pAb, Rabbit, Polyclonal
• Biozol Catalog Number: EBT-ES8518
• Supplier Catalog Number: ES8518
• Alternative Catalog Number: EBT-ES8518-50, EBT-ES8518-100
• Manufacturer: ELK Biotechnology
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Species Reactivity: Human, Rat
• Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420
• Alternative Names: Complement component C8 beta chain (Complement component 8 subunit beta)

Product Description

This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: 70kD
• NCBI: 732
• UniProt: P07358

Application Notes

• Application Dilute: WB 1:500-2000, ELISA 1:10000-20000

Images

Western Blot analysis of 3T3 HEPG2 cells using C8 beta Polyclonal Antibody diluted at 1:2000. Secondary antibody(catalog:RS0002) was diluted at 1:20000