FAT1 rabbit pAb, Rabbit, Polyclonal

Catalog Number: EBT-ES9143
Article Name: FAT1 rabbit pAb, Rabbit, Polyclonal
Biozol Catalog Number: EBT-ES9143
Supplier Catalog Number: ES9143
Alternative Catalog Number: EBT-ES9143-50, EBT-ES9143-100
Manufacturer: ELK Biotechnology
Host: Rabbit
Category: Antikörper
Application: IF, IHC
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human protein . at AA range: 1140-1220
This gene is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. This gene is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described. [provided by RefSeq, Jul 2008],
Clonality: Polyclonal
Concentration: 1 mg/ml
Molecular Weight: 504kD
NCBI: 2195
UniProt: Q14517
Application Dilute: IHC-p 1:50-300
Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4 overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).