Bradykinin B2 Antagonist (HOE 140)

Catalog Number: ECH-191-85
Article Name: Bradykinin B2 Antagonist (HOE 140)
Biozol Catalog Number: ECH-191-85
Supplier Catalog Number: 191-85
Alternative Catalog Number: ECH-191-85-1MG, ECH-191-85-5MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 138614-30-9 Molecular Weight: 1303.66 Salt Form: TFA Purity: >96% Sequence (3-letter): D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg-OH Sequence (1-letter): rRP(Hyp)G(Thi)S(D-Tic)(Oic)R-OH Storage: -20 ?C or below Bradykinin is a potent vasodilator peptide that exerts its action through stimulation of specific endothelial receptors. It has been linked with the pathophysiological process that accompanies tissue damage and inflammation. Bradykinin B2 Antagonist (HOE 140, Icatibant) has been shown to inhibit microvascualar leakage in a liver cirrhosis model. It also acts as an Aminopeptidase N inhibitor (Ki = 9.1 µM).
Application Notes: Categories: Peptides. Related: Neuropeptides & Hormones. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature