Endothelin 3, cyclic (human, mouse, rabbit, rat)

Product Overview

• Article Name: Endothelin 3, cyclic (human, mouse, rabbit, rat)
• Biozol Catalog Number: ECH-335-10
• Supplier Catalog Number: 335-10
• Alternative Catalog Number: ECH-335-10-0.5MG, ECH-335-10-1MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 117399-93-6 Molecular Weight: 2645.16 Salt Form: TFA Purity: >96% Sequence (3-letter): Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp-OH (Cys1-Cys15, Cys3-Cys11) Sequence (1-letter): CTCFTYKDKECVYYCHLDIIW-OH Storage: -20 ?C or below Solubility: water >1 mg/mL Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions. Endothelin-3 is an endogenous neuropeptide and potent vasoconstrictor. Endothelin-3 has been reported to attenuate thrombin-evoked aggregation of human platelets, acts as a potent stimulator of interleukin-6 production by endothelial cell lines, activates phospholipase C in fibroblasts expressing ETA receptors and induces the production of VEGF.

References

1. Baynash, A.G. (1994) ?Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons? Cell 79 (7): 1277?1285. 2. Matsumoto, H. et al. (1989) ?Abundance of endothelin-3 in rat intestine, pituitary gland and brain? 164 (1): 74-80. 3. Sakamoto, A. et al. (1991) ?Cloning and functional expression of human cDNA for the ETB endothelin receptor? Biochem. Biophys. Res. Commun. 178 (2): 656?663

Application Notes

• Application Notes: Categories: Peptides. Related: Cardiovascular, Neuropeptides & Hormones. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature