Gly-Arg-Gly-Asp-Ser (GRGDS)

Product Overview

• Article Name: Gly-Arg-Gly-Asp-Ser (GRGDS)
• Biozol Catalog Number: ECH-450-38
• Supplier Catalog Number: 450-38
• Alternative Catalog Number: ECH-450-38-1MG,ECH-450-38-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 96426-21-0 Molecular Weight: 490.21 Salt Form: TFA Purity: >96% Sequence (3-letter): Gly-Arg-Gly-Asp-Ser-OH Sequence (1-letter): GRGDS-OH Storage: -20 ?C or below Solubility: water or 5% acetic acid GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin. Osteopontin uses this motif for cell adhesion. This peptide includes the RGD (Arg-Gly-Asp) sequence found in many extracellular matrix adhesive proteins. GRGDS is a synthetic antagonist of integrin function and competitively inhibits direct fibroblast binding to fibronectin.

References

1.Miyamoto, S., Akiyama, S.A. and Yamada, K.M. (1995) ?Synergistic Roles for Receptor Occupancy and Aggregation in Integrin Transmembrane Function? Science 267 (5199): 883-885. 2. Denhardt, D.T. and Guo, X. (1993) ?Osteopontin: a protein with diverse functions? FASEB J. 7: 1475-1482.

Application Notes

• Application Notes: Categories: Peptides. Related: Cardiovascular, Fibrinogen. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature