Caerulein (ceruletide)

Product Overview

• Article Name: Caerulein (ceruletide)
• Biozol Catalog Number: ECH-471-65
• Supplier Catalog Number: 471-65
• Alternative Catalog Number: ECH-471-65-1MG, ECH-471-65-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 17650-98-5 Molecular Weight: 1351.44 Salt Form: N/A Purity: >96% Sequence (3-letter): Glp-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2 Sequence (1-letter): (Glp)QD(Tyr(SO3H))TGWMDF-NH2 Storage: -20 ?C or below Solubility: water, >1 mg/mL Caerulein is a sulfated peptide that is used in the study of NF-?B-mediated signaling. When administered via i.v., it can produce analgesia. It has also been shown to induce pancreatitis in animals at high doses and prevent pain associated with gall-bladder contraction and intermittent claudication. Glp = Pyroglutamic acid

References

1. Baber, N.S., Dourish, C.T. and Hill, D.R. (1989) ?The role of CCK, caerulein, and CCK antagonists in nociception? Pain 9: 307-328. 2.Watanabe, O. et al (1984) ?Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis? Am. J. Physiol. 246(4 Pt 1): G457-67.

Application Notes

• Application Notes: Categories: Peptides. Related: Gastrointestinal. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature