Molecular Weight: 673.3Salt Form: N/APurity: >96%Sequence (3-letter): Ac-Leu-Glu-Val-Asp-AMCSequence (1-letter): Ac-LEVD-AMCStorage: -20 AC or belowAc-Leu-Glu-Val-Asp-AMC is a fluorogenic substrate for Caspase 4. Caspase 4 is a cysteine protease with a poorly defined role in the caspase family. Recent studies have shown it to have a role in inflammation and innate immunity. Like all caspases it cleaves at the Asp residue and prefers the sequence Leu-Glu-Val-Asp.Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.
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1208 1179
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