Ac-Leu-Glu-Thr-Asp-AFC (Caspase 8 Substrate), CAS [[210345-02-1]]

Catalog Number: ECH-863-44-25MG
Article Name: Ac-Leu-Glu-Thr-Asp-AFC (Caspase 8 Substrate), CAS [[210345-02-1]]
Biozol Catalog Number: ECH-863-44-25MG
Supplier Catalog Number: 863-44-25mg
Alternative Catalog Number: ECH-863-44-25MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 210345-02-1Molecular Weight: 729.67Salt Form: N/APurity: >96%Sequence (3-letter): Ac-Leu-Glu-Thr-Asp-AFCSequence (1-letter): Ac-LETD-AFCStorage: -20 AC or belowAc-Leu-Glu-Thr-Asp-AFC is a fluorogenic substrate for caspase 8. Caspase 8 is a cysteine protease involved in apoptosis induced by Fas and other stimuli. It is an attractive therapeutic target for a variety of degenerative disorders.Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.
Tag: 1208 1179
CAS Number: [210345-02-1]