Caspase 6 (Mch2) Substrate, fluorogenic

Product Overview

• Article Name: Caspase 6 (Mch2) Substrate, fluorogenic
• Biozol Catalog Number: ECH-863-52
• Supplier Catalog Number: 863-52
• Alternative Catalog Number: ECH-863-52-25MG, ECH-863-52-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Molecular Weight: 727.27 Salt Form: N/A Purity: >96% Sequence (3-letter): Ac-Val-Glu-Ile-Asp-AFC Sequence (1-letter): Ac-VEID-AFC Storage: -20 ?C or below Solubility: 20 mM in DMSO or DMF Ac-VEID-AFC is a fluorogenic substrate for caspase 6 (Mch-2?), a member of the cysteine-aspartate protease family, which play a central role in the execution-phase of apoptosis. The excitation/emission maximum of AFC is 400/505 nm, respectively. Ac-VEID-AFC is based on lamin A site of cleavage.

References

1. LeBlanc, A. et al. (1999) ?Caspase-6 Role in Apoptosis of Human Neurons, Amyloidogenesis, and Alzheimer?s Disease? J. Biol. Chem. 274: 23426-23436. 2. Guo, R-F. et al. (2000) ?Protective effects of anti-C5a in sepsis-induced thymocyte apoptosis? J. Clin. Invest. 106(10): 1271?1280.

Application Notes

• Application Notes: Categories: Peptides. Related: Caspase, Enzyme Substrates. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature