Z-Ile-Glu-Thr-Asp-AFC (Granzyme B Substrate), CAS [[219138-02-0]]

Catalog Number: ECH-863-56-5MG
Article Name: Z-Ile-Glu-Thr-Asp-AFC (Granzyme B Substrate), CAS [[219138-02-0]]
Biozol Catalog Number: ECH-863-56-5MG
Supplier Catalog Number: 863-56-5mg
Alternative Catalog Number: ECH-863-56-5MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 219138-02-0Molecular Weight: 821.76Salt Form: N/APurity: >96%Sequence (3-letter): Z-Ile-Glu-Thr-Asp-AFCSequence (1-letter): Z-IETD-AFCStorage: -20 AC or belowZ-IETD-AFC is a fluorogenic substrate for Granzyme B. Granzyme B is a serine protease found in cytotoxic T-cells and NK cells. It cleaves and activates several caspases involved in apoptosis.Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.
Tag: 1208 1179
CAS Number: [219138-02-0]