Caspase 3 (Apopain) Inhibitor

Product Overview

• Article Name: Caspase 3 (Apopain) Inhibitor
• Biozol Catalog Number: ECH-864-20
• Supplier Catalog Number: 864-20
• Alternative Catalog Number: ECH-864-20-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 184179-08-6 Molecular Weight: 502.19 Salt Form: N/A Purity: >96% Sequence (3-letter): Ac-Asp-Glu-Val-Asp-CHO Sequence (1-letter): Ac-DEVD-CHO Storage: -20 ?C or below Solubility: 13.7 mg/ml in DMSO Caspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent, reversible inhibitor of caspase-3 (Ki < 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent.

References

1. Talanian, R.V. et al (1997) ?Substrate Specificities of Caspase Family Proteases? 272 (15): 9677?9682. 2. Godinat, A. et al. (2013) ?A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice? ACS Chemical Biology 8 (5): 987-999.

Application Notes

• Application Notes: Categories: Peptides. Related: Caspase, Inhibitor. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature