Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH (Caspase 1 Substrate), CAS [[189696-01-3]]

Product Overview

• Article Name: Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH (Caspase 1 Substrate), CAS [[189696-01-3]]
• Biozol Catalog Number: ECH-865-21-1MG
• Supplier Catalog Number: 865-21-1mg
• Alternative Catalog Number: ECH-865-21-1MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 189696-01-3Molecular Weight: 1144.43Salt Form: N/APurity: >96%Sequence (3-letter): Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OHSequence (1-letter): (Mca)YVADAP(Lys(DNP))-OHStorage: -20 AC or belowMca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH is a FRET substrate for caspase 1. Caspase 1/Interleukin 1b converting enzyme (ICE) is a cysteine protease that preferentially cleaves substrates built on VAD (val-ala-asp) or WEAD (trp-glu-ala-asp) sequences.A ICE converts inactive IL-1 beta precursor to a pro-inflammatory cytokine that mediates a wide range of immune and inflammatory response.A ICE-related cysteine proteases are required for E1A-induced p53-dependent apoptosis in baby rat kidney (BRK) cells. Adenovirus E1B 19K protein which is a potent inhibitor of apoptosis inhibits activation of these proteases in BRK cells.Activity can be continuously measured by excitation at 325nm and emission at 392 nm

Product Properties

• Tag: 1179
• CAS Number: [189696-01-3]