Cathepsin L Inhibitor (RKLLW-NH2), CAS [[289480-71-3]]

Catalog Number: ECH-866-23-5MG
Article Name: Cathepsin L Inhibitor (RKLLW-NH2), CAS [[289480-71-3]]
Biozol Catalog Number: ECH-866-23-5MG
Supplier Catalog Number: 866-23-5mg
Alternative Catalog Number: ECH-866-23-5MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 289480-71-3Molecular Weight: 713.47Salt Form: TFAPurity: >96%Sequence (3-letter): Arg-Lys-Leu-Leu-Trp-NH2Sequence (1-letter): RKLLW-NH2Storage: -20 AC or belowCathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker for A cancer progression. The inhibitor has a low micromolar IC50.References:1) A. Brinker et al. (2000) Highly potent inhibitors of human cathepsin L identified by screening combinatorial pentapeptide amide collections Eur. J. Biochem. 267 5085-5092.
Tag: 172
CAS Number: [289480-71-3]