Z-Phe-Arg-AFC (Cathepsin L Substrate), CAS [[65147-22-0]]

Product Overview

• Article Name: Z-Phe-Arg-AFC (Cathepsin L Substrate), CAS [[65147-22-0]]
• Biozol Catalog Number: ECH-866-75-10MG
• Supplier Catalog Number: 866-75-10mg
• Alternative Catalog Number: ECH-866-75-10MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 65147-22-0Molecular Weight: 666.24Salt Form: TFAPurity: >96%Sequence (3-letter): Z-Phe-Arg-AFCSequence (1-letter): Z-FR-AFCStorage: -20 AC or belowZ-Phe-Arg-AFC is a fluorogenic for Cathepsin L. Cathepsin L is a lysosomal cysteine protease with an important role in initiating protein degradation. Cathepsin L is also upregulated in several cancers and has been suggested as a drug target. In addition A extracellular secretion of Cathepsin L by tumors implicates it as a potential serum biomarker forA cancer progression.Activity is quantified by release of free fluorescent 7-amino-4-trifluoromethylcoumarin (AFC) which excites at 395-400 nm and emits at 495-505 nm.

Product Properties

• Tag: 1179
• CAS Number: [65147-22-0]