Cathepsin S Substrate fluorogenic, CAS [[1135686-31-5]]

Catalog Number: ECH-866-80-1MG
Article Name: Cathepsin S Substrate fluorogenic, CAS [[1135686-31-5]]
Biozol Catalog Number: ECH-866-80-1MG
Supplier Catalog Number: 866-80-1mg
Alternative Catalog Number: ECH-866-80-1MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 1135686-31-5Molecular Weight: 870.51Salt Form: TFAPurity: >95%Sequence (3-letter): Ac-Lys-Gln-Lys-Leu-Arg-AMCSequence (1-letter): Ac-KQKLR-AMCStorage: -20 AC or belowAc-KQKLR-AMC is a fluorogenic substrate for Cathepsin S. Cathepsin S is a lysosomal cysteine protease with important roles in MHC Class II antigen presentation and nociception. Cathepsin S also cleaves several extracellular matrix proteins (laminin fibronectin elastin osteocalcin) and glycosaminoglycans (heparin sulfate chondroitin sulfate).Activity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm.
Tag: 1179
CAS Number: [1135686-31-5]