PKC Isoenzyme Inhibitor (myristoylated)

Product Overview

• Article Name: PKC Isoenzyme Inhibitor (myristoylated)
• Biozol Catalog Number: ECH-880-17-1MG
• Supplier Catalog Number: 880-17-1mg
• Alternative Catalog Number: ECH-880-17-1MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Molecular Weight: 880.17Salt Form: TFAPurity: >95%Sequence (3-letter): N-Myr-Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OHSequence (1-letter): (Myristoyl)EAVSLKPT-OHStorage: -20 AC or belowProtein kinase C epsilon PKC(e) is involved in the regulation of diverse cellular functions including neurotransmitter release in the brain. Translocation of PKC(e) is a marker of activity and can be blocked with isozyme specific peptides. This peptide is the myristoylated version of an octapeptide PKC(e) inhibitor (Cat 880-15). Glu-Ala-Val-Ser-Leu-Lys-Pro-Thr-OH is a selective inhibitor of the translocation of PKC(e). It can be used to resolve the functions of PKC(e) from those of other PKC isozymes.ReferencesObisA et al. (2015) The novel protein kinase C epsilon isoform at the adult neuromuscular synapse: location regulation by synaptic activity-dependent muscle contraction through TrkB signaling and coupling to ACh release. Molecular Brain (8)