MG-115 (Proteasome Inhibitor)

Product Overview

• Article Name: MG-115 (Proteasome Inhibitor)
• Biozol Catalog Number: ECH-882-10
• Supplier Catalog Number: 882-10
• Alternative Catalog Number: ECH-882-10-5MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

CAS Number: 133407-86-0 Molecular Weight: 461.29 Salt Form: N/A Purity: >96% Sequence (3-letter): Z-Leu-Leu-Nva-CHO Sequence (1-letter): Z-LL(Nva)-CHO Storage: -20 ?C or below MG-115 (Z-Leu-Leu-Nva-CHO) is a potent, cell permeable inhibitor of the 20S proteosome. It forms a reversible hemiacetal adduct and can also inhibit cathepsins and calpains. It reduces degradation of ubiquitinated proteins and blocks proteolytic conversion of protein precursors. MG-115 is known to induce the heat shock response and apoptosis.

References

Rock, K.L., Gramm, C., Rothstein, L.,?et al. (1994) Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules.?Cell?78,?761-771.

Application Notes

• Application Notes: Categories: Peptides. Related: Inhibitor. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature