Pancreatic Elastase Substrate, colorimetric

Catalog Number: ECH-883-18
Article Name: Pancreatic Elastase Substrate, colorimetric
Biozol Catalog Number: ECH-883-18
Supplier Catalog Number: 883-18
Alternative Catalog Number: ECH-883-18-10MG,ECH-883-18-5MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 52299-14-6 Molecular Weight: 451.17 Salt Form: N/A Purity: >96% Sequence (3-letter): Suc-Ala-Ala-Ala-pNA Sequence (1-letter): Suc-AAA-pNA Storage: -20 ?C or below Solubility: DMSO >5 mg/mL, can be further diluted into neutral pH buffer Suc-AAA-pNA is a sensitive substrate for human, rat leukocyte and porcine pancreatic elastases. Reactions are monitored by measuring an increase in the absorbance signal at 405-410 nm. Suc-AAA-pNA is also hydrolyzed by proteinase K, subtilisins and thermitase.

References

1. L?demann, J., Utecht, B. and Gross, W.L. (1990) ?Anti-neutrophil cytoplasm antibodies in Wegeners granulomatosis recognize an elastinolytic enzyme? J. Exp. Med. 171 (1): 357-362. 2. B?ckle, B. Galunsky, B. and M?ller, R. (1995) ?Characterization of a keratinolytic serine proteinase from Streptomyces pactum DSM 40530? Appl. Environ. Microbiol. 61 (10): 3705-3710. 3. Chen, Z. et al. (1992) ?Purification and characterization of a 50-kDa cysteine proteinase (gingipain) from Porphyromonas gingivalis? 267: 18896-18901.
Application Notes: Categories: Peptides. Related: Enzyme Substrates. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature