Calmodulin Kinase II Inhibitor (281-309)

Catalog Number: ECH-893-40
Article Name: Calmodulin Kinase II Inhibitor (281-309)
Biozol Catalog Number: ECH-893-40
Supplier Catalog Number: 893-40
Alternative Catalog Number: ECH-893-40-1MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
Molecular Weight: 3371.86 Salt Form: Acetate Purity: >96% Sequence (3-letter): Met-His-Arg-Gln-Glu-Thr-Val-Asp-Cys-Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala-OH Sequence (1-letter): MHRQETVDCLKKFNARRKLKGAILTTMLA-OH Storage: -20 ?C or below Calmodulin Kinase II Inhibitor (281-309) [CaMKII(281-309)] is a peptide fragment containing the calmodulin binding site (290-309) and the phosphorylation site (Thr286). CaMKII(281-309). It is useful as a calmodulin binding peptide and can act as an inhibitor of CaM kinase II (IC50?= 80 nM) by blocking Ca2+/calmodulin activation and enzyme active site. Alternative name: Calmodulin Dependent Protein Kinase II (281-309)

References

Waxham MN, Aronowski J (1993) Ca2+/calmodulin-dependent protein kinase II is phosphorylated by protein kinase C in vitro. Biochemistry 32(11):2923-30
Application Notes: Categories: Peptides. Related: Kinase. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature