Extracellular Death Factor

Catalog Number: ECH-950-10
Article Name: Extracellular Death Factor
Biozol Catalog Number: ECH-950-10
Supplier Catalog Number: 950-10
Alternative Catalog Number: ECH-950-10-1MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
CAS Number: 960129-66-2 Molecular Weight: 660 Salt Form: TFA Purity: >95% Sequence (3-letter): Asn-Asn-Trp-Asn-Asn-OH Sequence (1-letter): NNWNN-OH Storage: -20 ?C or below Extracellular death factor (EDF) is a linear pentapeptide that activates the cell death pathway in a subset of communicating cells. Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. It is sensitive to extreme pH, high temperatures, and other cellular stress. EDF has been shown to trigger cell death at 2.5 ng/ml which significantly reduces population size in some E. coli cultures.

References

Belitsky M, Avshalom H, Erental A, Yelin I, Kumar S, London N, Sperber M, Schueler-Furman O, Engelberg-Kulka H (2011) The Escherichia coli Extracellular Death Factor EDF Induces the Endoribonucleolytic Activities of the Toxins MazF and ChpBK Mol. Cell 41 (6) 625-635
Application Notes: Categories: Peptides. Related: Antimicrobial Peptide. Ship 1 : Shipping Temp. Ship 2: Ambient Temperature