BODIPY FL PI(3)P

Catalog Number: ECH-C-03F6
Article Name: BODIPY FL PI(3)P
Biozol Catalog Number: ECH-C-03F6
Supplier Catalog Number: C-03F6
Alternative Catalog Number: ECH-C-03F6-100UG,ECH-C-03F6-50UG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
BODIPY FL PI(3)P (BODIPY FL Phosphatidylinositol 3-phosphate) is a water soluble analog of PI(3)P labeled with the green fluorophore, Bodipy-FL at the sn-1 position.
Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3-phosphate is enriched in early endosomes having roles in endosome fusion and receptor sorting and internalization in multivesicular bodies. PI(3)P has also been found at the plasma membrane and is involved in the translocation of the glucose transport protein GLUT4.

Excitation/Emission

503/513 nm

Storage

-20 C, protect from light

Featured in Publications

1) Caromile, L. A., A. Oganesian, et al. (2010). The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion. J Biol Chem 285(14): 10487-96. 2)Rudge, S. A., D. M. Anderson, et al. (2004). Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Mol Biol Cell 15(1): 24-36. 3) Oganesian, A., M. Poot, et al. (2003). Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation. Proc Natl Acad Sci U S A 100(13): 7563-8. Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Application Notes: Categories: Lipids. Related: Fluorescent, PI(3)P. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination