GloPIPs BODIPY TMR-PI(3,4)P2

Product Overview

• Article Name: GloPIPs BODIPY TMR-PI(3,4)P2
• Biozol Catalog Number: ECH-C-34M6A
• Supplier Catalog Number: C-34M6A
• Alternative Catalog Number: ECH-C-34M6A-100UG,ECH-C-34M6A-50UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4-bisphosphate (PI(3,4)P2) is produced in stimulated cells by the action of phosphatidylinositol 3-kinases (PI3Ks) and/or lipid phosphatases (SHIP, TPTE, etc.). PI(3,4)P2 binds the pleckstrin homology (PH)-domain of AKT/PKB leading to cell survival and it also has an important role in podosome formation near focal adhesions.

---

GloPIPs are labeled at the sn-1 position with BODIPY-FL (505/513), BODIPY-TMR (544/574), or biotin. The sn-1 linkage in these labeled PIPs has been changed to a more stable amide from an ester. Results from experiments conducted at Echelon indicated that this minor chemical change did not have a significant effect in any of the applications tested. Bulk discounts available, please email echelon echelon-inc.com for information.

---

Documents

Technical Data Sheet

Application Notes

• Application Notes: Categories: Lipids. Related: Fluorescent, PI(3\,4)P2. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination