BODIPY TMR PI(4,5)P2

Product Overview

• Article Name: BODIPY TMR PI(4,5)P2
• Biozol Catalog Number: ECH-C-45M6
• Supplier Catalog Number: C-45M6
• Alternative Catalog Number: ECH-C-45M6-100UG,ECH-C-45M6-50UG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

BODIPY TMR PI(4,5)P2 (BODIPY TMR Phosphatidylinositol 4,5-bisphosphate) is a water soluble analog of PI(4,5)P2 (PIP2) labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.

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Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4,5-bisphosphate (PIP2) has been shown to play a central role in a variety of cellular functions. Amongst its many functions, PIP2 is a substrate for Phospholipase C-coupled G-protein pathways involved in intracellular calcium release in a number of tissues. It is also a substrate for class I phosphoinositide 3-kinase (PI3-K) forming PI(3,4,5)P3.

Excitation/Emission

542/574 nm

Storage

-20 C, protect from light

Featured in Publications

1) Cabanos C, Wang M, Han X, Hansen SB (2017) A Soluble Fluorescent Binding Assay Reveals PIP2 Antagonism of TREK-1 Channels. Cell Rep 20(6):1287-1294 Bulk discounts available, please email echelon echelon-inc.com for information.

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Documents

Technical Data Sheet

Application Notes

• Application Notes: Categories: Lipids. Related: Fluorescent, PI(4\,5)P2. Ship 1 : Shipping Temp. Ship 2: Dry ice or gel ice depending on destination