Cu(II) Protoporphyrin IX, CAS [[14494-37-2]]

Product Overview

• Article Name: Cu(II) Protoporphyrin IX, CAS [[14494-37-2]]
• Biozol Catalog Number: ECH-F-H070-50MG
• Supplier Catalog Number: F-H070-50mg
• Alternative Catalog Number: ECH-F-H070-50MG
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Cu (II) Protoporphyrin IX does not inhibit heme oxygenase (the enzyme that catalyzes the conversion of heme to biliverdin in the heme degradation pathway) and is used as a negative control for Zn (II) Protoporphyrin (an inihibitor of heme oxygenase).A Heme oxygenase has been implicated in tumor cell resistance to chemotherapy reduction of free radical formation and inflammation and associated with vascular repair.References1) Jozkowicz A. H. Was et al. (2007). Heme oxygenase-1 in tumors: is it a false friend? Antioxid Redox Signal 9(12): 2099-117.2) Abraham N. G. and A. Kappas (2005). Heme oxygenase and the cardiovascular-renal system. Free Radic Biol Med 39(1): 1-25.3) Kim D. H. A. P. Burgess et al. (2008). Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells. J Pharmacol Exp Ther 325(3): 833-40.

Product Properties

• Tag: 349
• CAS Number: [14494-37-2]