Dimethylallyl Diphosphate (DMAPP)

Catalog Number: ECH-I-0051
Article Name: Dimethylallyl Diphosphate (DMAPP)
Biozol Catalog Number: ECH-I-0051
Supplier Catalog Number: I-0051
Alternative Catalog Number: ECH-I-0051-10MG,ECH-I-0051-1MG
Manufacturer: Echelon Biosciences
Category: Molekularbiologie
Isoprenoid compounds are a diverse group of natural products which are essential components in all cells. Isoprenoids are biosynthesized from the simple precursors isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Eukaryotes, fungi, and some gram-positive bacteria produce IPP through the mevalonate (MVA) pathway whereas gram-negative and some gram-positive bacteria utilize the non-mevalonate or 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway.
Provided as the tris-ammonium salt

Featured in Publications

1. Burke, C. and R. Croteau (2002). Interaction with the small subunit of geranyl diphosphate synthase modifies the chain length specificity of geranylgeranyl diphosphate synthase to produce geranyl diphosphate. J Biol Chem 277(5): 3141-9. 2. Poliquin, K., Y. V. Ershov, et al. (2004). Inactivation of sll1556 in Synechocystis Strain PCC 6803 Impairs Isoprenoid Biosynthesis from Pentose Phosphate Cycle Substrates In Vitro. J Bacteriol 186(14): 4685-4693. 3. Schilmiller, A. L., I. Schauvinhold, et al. (2009). Monoterpenes in the glandular trichomes of tomato are synthesized from a neryl diphosphate precursor rather than geranyl diphosphate. Proceedings of the National Academy of Sciences 106(26): 10865-10870. 4. Haymond, A., et al. (2014). Kinetic Characterization and Allosteric Inhibition of the Yersinia pestis 1-Deoxy-D-Xylulose 5-Phosphate Reductoisomerase (MEP Synthase). PLoS ONE 9(8): e106243. 5. Gruenbacher, G., et al. (2016). Ecto-ATPase CD39 Inactivates Isoprenoid-Derived Vgamma9Vdelta2 T Cell Phosphoantigens. Cell Reports 16(2): 444-456. 6. Ma, Y., et al. (2019). Metabolic Engineering of the MEP Pathway in Bacillus subtilis for Increased Biosynthesis of Menaquinone-7. ACS Synthetic Biology 8(7): 1620-1630. Alternate Names: Dimethylallyl pyrophosphate, DMPP Bulk discounts available, please email echelon echelon-inc.com for information.

Documents

Technical Data Sheet
Application Notes: Categories: Biochemical Reagents. Related: Isoprenoid, Isoprenoid Diphosphate. Ship 1 : Shipping Temp. Ship 2: Gel Ice