Class III PI3K ELISA Kit

Product Overview

• Article Name: Class III PI3K ELISA Kit
• Biozol Catalog Number: ECH-K-3000
• Supplier Catalog Number: K-3000
• Alternative Catalog Number: ECH-K-3000-1KIT
• Manufacturer: Echelon Biosciences
• Category: Molekularbiologie

Product Description

Echelons Class III PI3K ELISA Kit is a competitive (96-well) ELISA assay kit that measures Class III Phosphoinositide 3-kinases activity directly through its reaction product, PtdIns(3)P (PI(3)P).

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Product Background

The Class III PI3K ELISA Kit is a competitive ELISA in which the signal is inversely proportional to the amount of PI(3)P produced. After the PI3-K reactions are complete, reaction products are added to the PI(3)P-coated microplate, for competitive binding to a PI(3)P detector protein. The amount of PI(3)P detector protein bound to the plate is determined through colorimetric detection.

Featured in Publications

1. Cao, X., et al. (2009). Thyroid-hormone-dependent activation of the phosphoinositide 3-kinase/Akt cascade requires Src and enhances neuronal survival. Biochem J 424(2): 201-209. 2. Mbengue, A., et al. (2015). A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria. Nature 520: 683-687. 3. Rajaram, M. V. S., et al. (2017). M. tuberculosis Initiated Human Mannose Receptor Signaling Regulates Macrophage Recognition and Vesicle Trafficking by FcRg-Chain, Grb2, and SHP-1. Cell Reports 21(1): 126-140. 4. Su, H., et al. (2017). VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy. Mol Cell 67(6): 907-921. 5. Singla, A., et al. (2019). Endosomal PI(3)P regulation by the COMMD/CCDC22/CCDC93 (CCC) complex controls membrane protein recycling. Nature Communications 10(1): 4271. Product Keywords: PI3K, PI3 Kinase, PI3 K, PI3-K, PI3P

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Documents

Technical Data Sheet PI3K Assay Comparison Guide

Application Notes

• Application Notes: Categories: Bioassays & Kits. Related: ELISA, Kinase. Ship 1 : Shipping Temp. Ship 2: Dry ice and / or gel ice depending on destination - product may ship in two boxes