Nitrooleic acid (OA-NO2) is formed by nitration of oleic acid from excessive nitric oxide during inflammation (nitrative stress). OA-NO2 is a potent signaling molecule which can activate numerous receptors including TRPA1 cation channels and PPARgamma. 9(10)-Nitrooleic acid is a mixture of the 9-nitro and 10-nitro isomers which are formed in equal amounts in vivo.
Storage
-20 C or below
References
1. P.S. Baker et al ''Fatty Acid Transduction of Nitric Oxide signaling Journal of Biological Chemistry, 2005, 280, 42464-42475, 2. F.J. Schopfer et al ''Covalent Peroxisome Proliferator-Activated Receptor Adduction By Nitro-Fatty Acid Journal of Biological Chemistry, 2010, 285, 12321-12333.
