LysoPC is generated through hydrolysis of the sn-2 acyl chain of PC by phospholipase A2. It is a major companent of oxidized low-density liporotein and is believed to have an important role in inflammatory diseases and atherosclerosis. LysoPC is the substrate for Autotaxin/LysoPLD generating lysophosphatidic acid which has an important role in cell motility.
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Categories: Lipids
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