S32826 [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt]
Catalog Number:
ECH-L-3282
Product Overview
Article Name:
S32826 [4-(Tetradecanoylamino)benzyl]phosphonic acid disodium salt]
Biozol Catalog Number:
ECH-L-3282
Supplier Catalog Number:
L-3282
Alternative Catalog Number:
ECH-L-3282-1MG,ECH-L-3282-5MG
Manufacturer:
Echelon Biosciences
Category:
Molekularbiologie
Product Description
S32826 is a potent inhibitor of the enzyme autotaxin, with an IC50 in the nanomolar range. S32826 is suitable for in vitro studies using purified components or cultured cells. Due to its short circulation half-life, S32826 is not recommended for use in animal models. Storage -20 C Featured in Publications 1) Ferry, G., N. Moulharat, et al. (2008). S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool. J Pharmacol Exp Ther 327(3): 809-19. 2) Conrotto, P., U. Andrasson, et al. (2011). Knock-down of SOX11 induces autotaxin-dependent increase in proliferation inA vitro and more aggressive tumors in vivo. Molecular Oncology 5(6): 527. 3) Li, S., C. Xiong, et al. (2012). ATX and LPA receptor 3 are coordinately up-regulated in lipopolysaccharide-stimulated THP-1 cells through PKR and SPK1-mediated pathways. FEBS Letters 586(6): 792. Documents Technical Data Sheet
Application Notes
Application Notes:
Categories: Biochemical Reagents. Related: Autotaxin, Inhibitor. Ship 1 : Shipping Temp. Ship 2: Gel Ice
